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Name: Ciprofloxacin hydrochloride / Ciprofloxacin HCL
C.A.S NO. : 86483-48-9
Synonyms: Ciprofloxacin Monohydrochloride
Molecular formula: C17H19ClFN3O3
Molecular weight : 367.802
Characteristic: White or yellowish crystalline powder
Solubility: Soluble in water, slightly soluble in methanol, insoluble in ethanol
Melting point: 318-320°C
| TERMS | SPECIFICATION |
| Appearance | Faintly yellowish to light yellow crystals. |
| A ,IR | IR spectrum of sample conforms to that of reference standard. |
| B ,HPLC | The retention time of the major peak of the sample solution corresponds to that of the standard solution,as obtained in the assay. |
| C Reaction of chlorides | A solution of it responds to the tests for chloride |
| Assay (on anhydrous basis) | 98.0%-102.0%of C17H18FN3O3.HCL |
| Residue on ignition | Not more than0.1% |
| Chloride and sulfate | |
| Sulfate | Not more than 0.04% |
| Heavy metals | Not more than 0.002% |
| Fluoroquinolonic acid | |
| (Method 1) | Not more than0.2% |
| Ciprofloxacin ethylenediamine analog (Method 2) | Not more than0.2% |
| Any other individual impurity | |
| (Method 2) | Not more than0.2% |
| Total impurities(Method 2) | Not more than0.5% |
| PH | 3.0 to 4.5 |
Ciprofloxacin hydrochloride / HCL is mainly used to treat:
1. Infection of the genitourinary system, including simple, complicated urinary tract infection, bacterial prostatitis, neisseria gonorrhea or cervicitis (including the production of enzyme strains).
2. Respiratory tract infection, including acute bronchial infection caused by sensitive gram-negative bacilli, and pulmonary infection.
3. Gastrointestinal tract infection, which is caused by shigella, salmonella, escherichia coli, hydrophilic aeromonas and parahaemolyticus.
4. Typhia.
5. Bone and joint infection.
6. Skin and soft tissue infection.
7. Septicemia and other systemic infections.
