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| Product Name: | Prednisone 21-acetate |
| CAS: | 125-10-0 |
| MF: | C23H28O6 |
| MW: | 400.46 |
| EINECS: | 204-726-0 |
| Product Categories: | Intermediates & Fine Chemicals;Pharmaceuticals;Steroids |
| Mol File: | 125-10-0.mol |
| TESTS | SPECIFICATIONS | RESULTS |
| Description | A white or almost white crystalline powder | A white crystalline powder |
| Specific rotation | Between +183°~+190° | +187.19° |
| Absorptivity | 373~397 | 382.46 |
| Identification | Reaction is red | Reaction is red |
| Become a turquoise | Become a turquoise | |
| Retention time is consistent with the retention time of the reference solution | Conforms | |
| IR absorption meets specification(Spectrum set 549 figure) | Conforms | |
| Related substances | Prednisone≤0.5% | 0.06% |
| Cortisone acetate≤1.5% | 0.56% | |
| Total impurities≤2.0% | 0.76% | |
| Loss on drying | ≤0.5% | 0.12% |
| Assay | 97.0~102.0% | 98.45% |
| Residual solvents | Ethanol≤5000ppm | 1056ppm |
| Ethyl acetate≤5000ppm | ND | |
| Packaging and storage | Store protected from light. | |
| CONCLUSION | Conform to CP2010 monograph | |
Prednisone Acetate Mainly used for a variety of acute serious bacterial infections, severe allergic disease, collagen diseases (lupus erythematosus, nodular influencing peripheral artery), rheumatism, rheumatoid arthritis, nephrotic syndrome, severe bronchial asthma, thrombocytopenia purpura, neutropenia, acute lymphoblastic leukemia, various adrenal insufficiency syndrome, exfoliative dermatitis, pemphigus, such as eczema. Elderly people with early onset of herpes zoster can be added with a small amount of prednisone to shorten the course and prevent the occurrence of postherpetic neuralgia.
