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Product Name: Sodium picosulfate
CAS: 10040-45-6
Assay: 99% min
MF: C18H13NO8S2.2Na
MW: 481.41
EINECS: 233-120-9
Appearance: Off-White Solid
Sodium picosulfate is a contact laxative used as a treatment for constipation or to prepare the large bowel before colonoscopy or surgery.
Orally administered sodium picosulfate is generally used for thorough evacuation of the bowel, usually for patients who are preparing to undergo a colonoscopy. It works very quickly, so access to a toilet at all times is recommended. It starts off by making bowel movements looser and more frequent, but within an hour or so of taking it the patient should experience diarrhea.
| Items | Specifications | Results |
| Appearance | White off-white crystalline powder | White off-white crystalline powder |
| Identification | Infared Absorption | Complies |
| The retention time of the major peak in the chromatogram of the Assay prepration corresponds to that in the chromatogram of the standard preparation, as obtained in the assay | complies | |
| Specific rotation | Between -28.6°and -35.0°, measured at 20° | -32.8° |
| Water | not more than 0.5% | 0.12% |
| residue on ignition | not more than 0.2% | 0.11% |
| Heavy metals | not more than 0.001% | complies |
| Particle size | 90% less than 350 microns | complies |
| Assay | 102.0% ocalculated with reference to the Anhydrous Basis | 99.8% |
| Conclustion | The material complies with respect to USP32 specifications | |
Pharmacetical raw material as antispasmodic agents.
This product is a smooth muscle relaxant. With inhibition of adenylate cyclase, the role of phosphodiesterase calcium antagonistic effect, and a weak anti-muscarinic effect on the smooth muscle of the genitourinary system selective spasm, which can be directly discharged urogenital system, smooth muscle spasm, and muscle relaxation, eliminating urinary frequency, urgency, incontinence and urinary bladder smooth muscle spasms caused by lower abdominal pain.
