1.Competitive price
2.Fast Delivery Within 2 days
3.SGS , BV, GMP,ISO approve
4.Professional factory
$3.80 - $4.00 / Kilogram
1 CAS: 107868-30-4
2 Trade names: Aromasin
3 Formula: C20H24O2
4 Mol. mass: 296.403 g/mol
5 Specification: Enterprise standard
6 Appearance: white crystalline powder
7 exemestane Assay: 99%
| Test Items | Specification | Results |
| Description | White Crystalline Powder | White Crystalline Powder |
| Identification | Positive | Positive |
| Assay(by HPLC) | 98.0~102.0% | 99.24% |
| Absorbance(E1cm) | 465~495 | 482.5 |
| Melting Point | 191~195°c | 193.5~195.0°c |
| Loss On Drying | 0.5%MAX | 0.19% |
| Specific Rotation | +288°~+298° | +290.2° |
| Residue On Ignition | 0.1%MAX | 0.03% |
| Related Substances | Total:1.5%MAX | <1.3% |
| Single:0.5%MAX | <0.4% | |
| Residue Solvents | 0.2%MAX | 0.10% |
| Heavy Metals | 20PPm max | <10PPm |
| Conclusion | The specification conform with enterprise standard. | |
Many breast cancers are stimulated to grow by the female sex hormones oestrogen and progesterone. These breast cancers are called hormone sensitive or hormone receptor positive and can be treated with drugs that block the effects of these hormones.
In women who have had their menopause, oestrogen is mainly produced by changing androgens (sex hormones produced by the adrenal glands) into oestrogens. This process is called aromatisation and happens mainly in the fatty tissues, muscle and the skin. It needs a particular enzyme called aromatase.
Exemestane blocks the process of aromatisation. So it lowers the amount of oestrogen in the body. In early breast cancer, taking exemestane can help to stop breast cancer coming back. In advanced breast cancer the cancer cells may grow more slowly or stop growing completely.
