CAS 1094-61-7 Purity 99.9% Beta-Nicotinamide Mononucleotide Nmn

Product Description:

Beta-Nicotinamide Mononucleotide

Nicotinamide mononucleotide (NMN), referred to as NMN, is a substance inherent in the human body and is also rich in some fruits and vegetables, including broccoli and cabbage. Use: In mammals, β-nicotinamide mononucleotide is generated by nicotinamide (Nam) under the catalysis of Nampt (a protease in the body), and then nicotinamide mononucleotide generates NAD+ under the catalysis of nicotinamide mononucleotide adenylyltransferase. Nicotinamide mononucleotide is a direct way to supplement NAD+. Nicotinamide mononucleotide achieves the effect of reversing aging by significantly improving the ability to repair DNA damage in cells. Nicotinamide mononucleotide will be converted into "nicotinamide adenine dinucleotide (NAD)", which is essential for energy metabolism in the body. In mouse experiments, it was confirmed that nicotinamide mononucleotide can activate a gene called acetylase in the body, thereby playing a role in prolonging life and treating diabetes. NAD is a substance that the human body can originally produce. Studies have confirmed that the content of NAD in the body will decrease with age. Application β-nicotinamide mononucleotide is the precursor of NAD+, a cofactor of longevity proteins in the human body. NAD+ is an important coenzyme in the tricarboxylic acid cycle, promoting the metabolism of sugars, fats, and amino acids, and participating in the synthesis of energy; NAD+ is also the only substrate of coenzyme I consuming enzymes (the only substrate of DNA repair enzyme PARP, the only substrate of longevity protein Sirtuins, and the only substrate of cyclic ADP ribose synthetase CD38/157). NAD+ participates in all aspects of human metabolism and is a key coenzyme. Without NAD+, metabolism will not work. Elderly people lack NAD+, so various major and minor problems come. By supplementing NAD+, comprehensive anti-aging can be achieved. Preclinical studies have shown that NMN has multiple pharmacological activities in cardiac and cerebral ischemia, Alzheimer's disease, type 2 diabetes and obesity caused by diet and age. As a precursor drug of NAD+, NMN mainly synthesizes NAD+ in the body to exert pharmacological effects, all of which are related to the lack of NAD+.