Children who don't grow up or are suffering from growth hormone deficiency
Growth hormone deficiency (GH) is a series of clinical manifestation syndrome caused by insufficient secretion or dysfunction of growth hormone (GH). The main characteristics are short stature, childish face, always like a little child. At present, there are 7 million children with growth hormone deficiency in China.
What is growth hormone deficiency?
Hypothalamus and pituitary, as the center of human endocrine system, can secrete a variety of hormones to regulate human growth and development. Growth hormone is one of them (growth hormone is a protein secreted by the anterior pituitary), which consists of 191 amino acids. It mainly promotes growth and development and material metabolism. It is the most important substance for human growth after birth.
Growth hormone deficiency (GHD) refers to a growth disorder caused by partial or total deficiency of growth hormone synthesized and secreted by the anterior pituitary, or by abnormal growth hormone structure and receptor deficiency. Generally, the growth hormone level of children with growth hormone deficiency is almost normal during the fetal period, but the growth of the children begins to slow down after birth. From childhood to adolescence, the growth of the children with growth hormone deficiency falls behind the normal children of the same age and sex.
Growth hormone deficiency (GHD) is one of the most common endocrine diseases in children.