How does insulin keep?

1. Therefore, for unopened insulin, no matter which kind of insulin is used, it should be stored in the refrigeration room of the refrigerator in the environment of 2 ~8 C. At this temperature, it maintains its biological effect and is sterile during its validity period.
2. Insulin in pen core should not be refrigerated

For the insulin that has been opened and is in use, it is necessary to distinguish between the pen core of the insulin pen or the bottled insulin that is sucked by the syringe.
If the latter is the case, because the bottle mouth is sealed with rubber, after extracting insulin, it can be put back into the refrigeration room of the refrigerator.
If the pen core is mounted in an insulin pen, it can not be put back into the refrigeration room after use.
The reason is not fear of insulin deterioration, but because there is a needle on the pen core, so that the insulin in the bottle is connected with the outside world. When the pen core is put into the refrigeration room, the temperature decreases and the liquid shrinks. Enter air into the pen core.  When taken out from the refrigeration room, the temperature rises, so that the insulin in the pen core overflows from the tip of the needle, which will affect the accuracy of the injection dose.
3. Preservation of Insulin in Use at Room Temperature

The unsealed bottled insulin and insulin pen core (after the injection needle pierces the rubber plug) can be stored for 30 days at normal room temperature (about 20 C, no more than 25 C-30 C). That's enough time for most sugar pals to safely run out of a whole bottle or a whole insulin.
Refrigeration is not recommended for insulin in use, because insulin products are more stable at room temperature, easier to mix, and make insulin injection more comfortable, and repeated changes in temperature will affect the efficiency of insulin.
4. Preservation in Special Environment
When traveling with insulin, you should avoid overcooling, overheating and repeated shocks. It is best to carry a thermal box with you. When traveling by air, insulin and other hypoglycemic drugs should be packed into the bags carried by the patients. They should not be checked with the baggage, because the baggage is easy to be lost and the temperature of the consignment cabin is too low, which will cause insulin degeneration.